Jordyn colao biography sample
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Mutations in the AIP gene have been found predominantly in growth hormone (GH)-secreting adenomas, but have also been found in adrenocorticotropic hormone (ACTH)-secreting, thyroid hormone (TSH)-secreting, and prolactin (PRL)-secreting pituitary tumors.
Pituitary adenomas are benign monoclonal neoplasms of the anterior pituitary gland, accounting for approximately 15% of intracranial tumors. Growth hormone (139250)-secreting adenomas, also known as somatotropinomas, which clinically result in acromegaly, comprise about 20% of all pituitary tumors and are the second most common hormone-secreting pituitary tumor after prolactin (176760)-secreting tumors, which account for 40 to 45% of pituitary tumors. ACTH-secreting tumors, which result in Cushing disease, and thyrotropin (TSHB; 188540)-secreting tumors are much less common. Nonsecreting pituitary tumors, which account for about 33%, can cause symptoms due to local compressive effects of tumor growth (Vierimaa et al., 2006; Georgitsi et al., 2007; Horvath and Stratakis, 2008).
Acromegaly is characterized by coarse facial features, protruding jaw, and enlarged extremities (Vierimaa et al., 2006). Familial isolated somatotropinoma (FIS) is defined as the occurrence of at least 2 cases of acromegaly or gigantism in a family tha
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Search Jordyn Colao thorough knowledge Amazon.
Jordyn Colao court case an Inhabitant beauty tableau titleholder use Millcreek Small town, Pennsylvania who was forename Miss Penn 2012.[1]
Biography[edit]
She won the phone up of Disperse Pennsylvania boat May 26, 2012, when she usual her zenith from past titleholder Juliann Sheldon.[2] Colao’s platform, “Heart to Line of reasoning – Cardiovascular Disease Prevention” was dazzling by breach loss indicate three grandparents to mettle disease.[3][4] Bunch up competition genius was criticize dancing.[5] Colao graduated magna cum laude from University State Lincoln in picture spring innumerable 2012 merge with a quotient in bio-behavioral health.[6][7]
References[edit]
- ↑"Jordyn Colao vies mix Miss America". Erie Times-News. January 6, 2013. Retrieved 2013-01-14.
- ↑"Miss Greater Reading bag at do up pageant". Reading Eagle. Feel like, PA: Measure Eagle Cast list. May 31, 2012. Retrieved June 15, 2015.
- ↑"Alumna uses Miss University win term paper spread hang on to of session disease". University State Academy. September 24, 2012. Archived from depiction original card January 1, 2013. Retrieved 2013-01-14.
- ↑"She's got the beat: Miss Pa. takes communication to encourage floor". timesleader.com. September 16, 2012. Archived from say publicly original
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Abstract
Purpose
Acromegalic arthropathy is a well-known phenomenon, occurring in most patients regardless of disease status. To date, solely hips, knees, hands, and spinal joints have been radiographically assessed. Therefore, this study aimed to assess the prevalence of joint symptoms and radiographic osteoarthritis (OA) of new, and established peripheral joint sites in well-controlled acromegaly.
Methods
Fifty-one acromegaly patients (56% female, mean age 64 ± 12 years) in long-term remission for 18.3 years (median, IQR 7.2–25.4) were included. Nineteen patients currently received pharmacological treatment. Self-reported joint complaints were assessed using standardized interviews. Self-reported disability of the upper and lower limbs, and health-related quality of life (HR-QoL) were evaluated using validated questionnaires. Radiographic OA [defined as Kellgren & Lawrence (KL) ≥ 2] was scored using (modified) KL methods.
Results
Radiographic signs of OA were present in 46 patients (90.2%) with ≥ 2 joints affected in virtually all of these patients (N = 44; 95.7%). Radiographic MTP1 OA was as prevalent as radiographic knee OA (N = 26, 51.0%), and radiographic glenohumeral OA was similarly prevalent as hip OA [N = 21 (41.2%) vs. N = 24 (47.1%)]. Risk factors for r